Update, 2:42 p.m., Friday: According to the Office of Media Relations at Stony Brook Medical Center University, Joseph Monaco is listed in fair condition.
Update, 1:15 p.m., Friday: Southold Police said on Friday that a Massachusetts woman was given a summons for failing to stop at a stop sign at Depot Lane in Thursday afternoon's incident which sent a Southold man to Stony Brook University Medical Center in a helicopter.
However since no contact was made between the two vehicles - Monaco swerved and dumped his bike without hitting the car - her vehicle was considered "uninvolved" in the accident.
According to Lt. James Ginas, 20-year-old Maryalice Fox was cited for failing to stop at a stop sign.
Update, 10:45 p.m.: Police said a Southold man driving a Harley-Davidson eastbound on Route 48 was hospitalized Thursday evening after attempting to avoid a car that didn't stop at a stop sign.
According to Southold Police, 72-year-old Joseph Monaco was airlifted to Stony Brook University Medical Center for treatment following the accident, which occurred just before 5 p.m.
Police stated via a release: "Monaco lost control of the motorcycle while attempting to avoid a collision with a second uninvolved vehicle that was northbound on Depot Lane and failed to stop at the stop sign."
Police did not release any further information about the second vehicle, and a desk officer said investigation of the incident is ongoing.
Original story: Route 48 re-opened around 7 p.m. following a crash Thursday afternoon.
A motor vehicle crash had shut down Route 48 in Cutchogue shortly before 5 p.m.
Police said the road is closed between Depot Lane and Cox Lane, though no further information was immediately available.
Check back with North Fork Patch as more information becomes available.